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APC: New Takes on an Old Gene

  • Marcy Richardson, PhD
  • March 28, 2024

A Brief History of APC The APC pathway was discovered in 1982 (more than 40 years ago!). APC is a tumor suppressor gene, meaning it helps the cell division process happen in a controlled way, which helps prevent tumor development. In 1991, Kinzler and Vogelstein discovered that pathogenic variants in the APC gene are …

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Transforming Fear into Action and Advocacy: Our Family’s Lynch Syndrome Story

  • Noelle Carbognin
  • March 22, 2024

It has been almost 3 years since my father was offered genetic testing after developing three different types of cancers. He also had an alarming family history – multiple relatives with cancer, going back generations. After he received a positive result for Lynch Syndrome, putting him at an increased risk for colon cancer and other types of …

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