Amy Byer Shainman, also known as BRCAResponder, is a patient advocate, author, and producer who provides support and education related to having a pathogenic variant in BRCA1/2 or other cancer predisposition genes. We connected with her ahead of National Previvor Day and Hereditary Breast and Ovarian Cancer Week. Amy’s sister was …
Are uncertain results (variants of uncertain significance, or VUS) more likely in multi-gene panels (MGP) or whole exome- and genome-based (WES/WGS) tests? Ambry recently participated in a study led by the Medical Genomic Initiative (MGI) comparing the VUS rates for MGP and WES/WGS. The study, conducted across 19 clinical laboratories in North …
Norma was a healthy, active 65-year-old woman who was rarely sick and had always been proactive about her health. She went to her internist complaining of weight gain, abdominal discomfort, and a chronic cough. When the diagnosis was finally made, Norma had stage 4 ovarian cancer. She endured nine hours of surgery, countless rounds of chemotherapy, …
Dr. Noel Boyd is an OB/GYN who has been in private practice in a suburb of Houston, TX, for 21 years. The patients seen in her practice, Her Healthcare, range in age from 9 to 99, and she cares for them through everything from routine exams to high-risk pregnancy, from contraception counseling to cancer screening. “I really love taking care …
Ben Huebsch was inspired to become an educator because of his mother’s advice to give back to his community. He loves his job as a middle school principal: he gets a front-row seat to the impact a dedicated staff can have on young lives! He is continuing his mother’s legacy by sharing his firsthand experience with BRCA testing for …
This week, we are celebrating the tenth anniversary of the Supreme Court’s decision, Association of Molecular Pathology versus Myriad Genetics (“Myriad") that overturned the validity of gene patents. The case was successful, because of some remarkable contingencies, first the conceptualization by ACLU lawyer Chris Hansen and his advisor Tania …
When it comes to breast cancer, Runi Limary has more personal experience than average. She not only spent time working at a nonprofit for people with breast cancer, but she was diagnosed herself at the young age of twenty-eight. When ACLU lawyers reached out to her about the court case regarding BRCA1 and BRCA2 patents to …
Morgan Turpin, MB(ASCP), CGMBS, Technical Systems Manager, is an Ambry Genetics employee who has firsthand knowledge of the benefits of exome testing. Her son Shayne went through a diagnostic odyssey of his own before he was a toddler. Exome testing opened up many possibilities for the family, including an online community and treatment options. …
Meet the Gene Team The Gene Team is an essential part of Ambry Genetics. This passionate team of experts is inspired by advancing the science of gene characterization and being able to help patients. For our third installment, we would like to introduce Jennifer Huang, PhD, Senior Clinical Scientist at Ambry Genetics. Dr. Jennifer Huang is …
Ambry Genetics caught up with Robert Pilarski, MS, LGC, MSW, Director of Medical Affairs, at his home on the shore in Cape Cod. He describes the town as “his happy place,” and in learning more about his role at Ambry, it seems that his career has entered a happy place as well. Rob has been with Ambry for over two years and is often sought …
Meet the Gene Team The Gene Team is an essential part of Ambry Genetics. This passionate team of experts is inspired by advancing the science of gene characterization and being able to help patients. For our second installment, we would like to introduce Jeni Herrera-Mullar, MGC, CGC, DMA, Principal Clinical Scientist at Ambry Genetics. Jeni is …
In recognition of Colon Cancer Awareness Month, Ambry would like to share the story of Jane and Julie Smith (not their real names) – sisters and cancer survivors. Jane was diagnosed with colon cancer in 2004 at the age of 36. While she was concerned about her diagnosis and family history of ovarian cancer, genetic testing was not widely available …
Being a “woman of substance” requires a passion for benefitting the greater good. Dr. Cathrine Keller has it in abundance. “We believe the greater good is to put our patients’ health and safety at the epicenter of every decision we make.” A woman of substance seldom has a neutral position. As a leader in the fight against breast cancer, …
Meet the Gene Team The Gene Team is an essential part of Ambry Genetics. This passionate team of experts is inspired by advancing the science of gene characterization and being able to help patients. For our first installment, we would like to introduce Bess Wayburn, PhD, CGC, Principal Clinical Scientist at Ambry Genetics. Bess Wayburn …
Earlier this year, the nation’s attention was captured by Damar Hamlin’s story after he collapsed on the field from sudden cardiac arrest (SCA) during Monday Night Football. After Hamlin’s collapse, teammates, fans and most of America watched as CPR was performed and he was taken to the hospital in an ambulance. In the days that followed, …
The adage “knowing is half the battle” describes Trinity Chappelear perfectly. Her dear friend Brandi Preston lost her mother to breast cancer at age 14, spurring Preston to start The Kamie K Preston Hereditary Cancer Foundation, based in Omaha, Nebraska. The non-profit is devoted to educating and supporting awareness for genetic testing to …
My Faulty Gene is a nonprofit organization that provides information and assistance to individuals whose family medical history suggests genetic testing might be helpful in identifying an increased risk of disease due to a genetic mutation. They believe that everyone in need of genetic testing should have access to it. We sat down with Kathy …
“It’s one thing to be scared to hear something, it’s another to die from not hearing something at all.”—Rick, Colon & Kidney Cancer Survivor (American Cancer Society) When I was twelve years old, my cousin was diagnosed with Stage 4 colon cancer. She was only 24. My mother knew my grandfather on …
“Genetic counselor” is not just a job title, though it is one that I have been enormously proud to carry for the past 10 years. In that time, I have come to primarily think of “genetic counselor” as a term which embodies a skill set. Just like Liam Neeson in “Taken,” we have a very special set of skills, however, our skills allow …
Ambry was founded with one goal– help patients and families. It is with this goal in mind that we design every test, accession every sample, interpret every result, and generate every report. Prior to becoming CEO at Ambry, I held various positions here, including Chief Scientific Officer for 5 years. Our motto is to design, validate and perform …
As a genetic counselor, creating a family history is one of my greatest tools for clinical practice. It helps me assess an individual’s risk for a particular genetic condition, establish rapport with my patient, and educate on the features and variability of a genetic condition. For many years, family history was a manual process, where stencils …
Whole exome sequencing (WES) is an efficient way to identify genetic variants in all of an individual's genes. It does this by sequencing the functionally relevant regions of approximately 20,000 genes of the human genome. Compared to traditional genetic testing trajectory, which tends to be more time-consuming, recent studies indicate WES can …
As a clinical genetic counselor, I saw many cancer survivors for genetic counseling. In some cases, it had been 30-40 years since they were diagnosed. Some of them were in their 60s-70s when I saw them, but they were young at the time of their cancer diagnosis. Years later, they were referred to me to talk about the possibility that their …
There has been a lot of talk about Direct-To-Consumer (DTC) genetic testing and the caveats that come along with that type of testing, but what does it all really mean? What is the actual difference between a DTC genetic test and a genetic test ordered by a medical professional through a clinical laboratory? There are several things that make …
The explosion of direct-to-consumer genetic testing over the last few years has created a ton of buzz, beyond just ancestry, health traits and wine preferences. Many of these DTC labs also release raw data to the consumer; this often leaves many individuals interested in what these findings mean and their potential impact on their healthcare …
Many people have friends and family members who tell stories of losing their father when he was 40, or having a mother who had a heart attack in her 30s. These same people may even know that they have high cholesterol, and sometimes are told it is inherited. What they don’t know is that this condition could be familial hypercholesterolemia (FH) …
There are many factors that impact your patients’ risk to develop certain cancers, including whether or not they have a family history of the disease, which can significantly impact the likelihood they may develop cancers such as breast, colorectal, and prostate. Individuals with a strong family history of cancer may have a hereditary cancer …
Editor’s Note: Science in 60 is a new video series from Ambry in which our researchers will give a brief overview of how genetic testing can help everyone understand disease. In this inaugural segment, Ambry genetic counselor Tami Johnston, MS CGC, looks at how genetic testing can improve the diagnoses and treatment plans for patients with …
After watching my mom and aunt battle bilateral breast cancer - which included chemotherapy, radiation, mastectomies (surgical removal of the breast(s)), and all the physical and emotional anguish that accompanies it – I learned that I carry a BRCA2 gene mutation. It runs in our family. I was told that my inherited BRCA2 mutation …
From consumers, to physicians to genetic counselors, the importance of heart health is taking center stage in genetics. Clinicians from all specialties are recognizing the benefits of cardiovascular genetic testing; inherited arrhythmias, cardiomyopathies, thoracic aortic aneurysms, and familial hypercholesterolemia are becoming more commonly discussed …
Ambry Celebrates a Milestone Year Ambry is looking forward to an exciting 2018, after experiencing a year of reaching important milestones and seeing many changes in 2017. From joining the Konica Minolta family, to the launch of our paired testing in our mission to understand all disease, to say it was a busy year is an understatement. Test Launches Ambry …
It has been an exciting and busy year at Ambry Genetics, packed with steps forward on our path towards understanding all human disease. We have continued our dedication, not only to quality testing, but to innovation, research, and patient advocacy. As we reach the end of 2017, we look forward to an even more impactful 2018 and working together …
*Editor's Note: In honor of Family History Day, which is on Thanksgiving, Eve Mart is sharing the story how hereditary cancer has shaped her relationship with her mother, and how genetic testing may have been able to help change the course of her mother's health. I often tell women “be your own best advocate”, and I truly mean …
In our more than 20 years of operation, Ambry has come a long way. Looking back, it’s important to remember that we would not be “Ambry Genetics” without our genetic counselors. Ambry is built on the foundation of quality genetic testing that helps people find answers – and genetic counselors have been with us from the beginning, working …
Our daughter Daphne started missing developmental milestones at around 6 months of age. She was unable to sit on her own and unwilling to eat baby food. We started down the path of diagnosis, which was long and exhausting and went like this: First, we went to our pediatrician to document our initial concerns and obtain referrals for a physical …
Ambry strives to always present impactful research that moves the science of genetics forward at tradeshows and conferences throughout the year. Below, are summaries of the research we presented at this year's American Society of Human Genetic's Annual Meeting. Black, M.H., et al: Type 2 Diabetes Variants Contribute to Breast Cancer …
An estimated 252,710 women will be diagnosed with breast cancer in 2017.1 Early detection of breast cancer is critical for successful treatment of this disease - women who are diagnosed with early stage/localized breast cancer have a 5-year survival rate of 98.9% 1 We hope that this Breast Cancer Awareness Month will inspire more people to discuss …
Lynch syndrome is one of the most common hereditary cancer syndromes, affecting about 1/279-1/440 people in the U.S. It is caused by a genetic mutation in one of five genes: MLH1, MSH2, MSH6, PMS2, or EPCAM. Individuals with Lynch syndrome have a significantly increased lifetime risk for multiple types of cancer including colorectal …
In our quest to understand all human disease, Ambry employs a team of researchers who investigate topics from every area of genetics research. Throughout her tenure at Ambry, Zoe Powis, MS CGC, Supervisor of Clinical Genomics Research, has contributed much to the broader body of knowledge about the field of genetics. At this year’s National …
We present impactful research to move the science of genetics forward at tradeshow and conferences throughout the year. Check out some of the research, separated by category below, that we brought to this year’s National Society of Genetic Counselor’s annual meeting. Read about the contributions from our lead researcher Zoe Powis and the …
Just five short years ago, hereditary cancer testing was much simpler for patients and healthcare providers. There were finite criteria, associated with a handful of genetic conditions, and healthcare providers could order single-gene (or single-syndrome) genetic testing for patients who met those criteria. Since 2012, the field of genetics …
An estimated 22,440 women will be diagnosed with ovarian cancer in 2017. Early detection is critical for successful treatment of this disease, which has a 5-year survival rate of 92.5% for women who are diagnosed with early stage/localized ovarian cancer.1 We hope that Ovarian Cancer Awareness Month will bring more women to their healthcare providers …
An estimated 161,360 men will be diagnosed with prostate cancer in 2017; early detection is critical for successful treatment of this disease. We hope that Prostate Cancer Awareness Month will bring more men to their healthcare providers asking about prostate cancer screening or about their risk of developing this disease. Genetic testing for …
At Ambry, we believe working together is better, that sharing data is essential to finding answers faster. Our scientists embody these beliefs by collaborating with other talented researchers and physicians to understand human disease, most recently in epilepsy genetics. We are proud to have contributed to the clinical research reviewed …
Germline genetic testing is used by many labs to evaluate a patient’s predisposition to hereditary cancer, and produces excellent results in its analysis of many genetic conditions. However, when germline testing is combined with tumor testing as a single paired test, it may yield even more helpful results in certain situations. Specifically, …
*Editor's Note: This post was originally shared on June 8th, 2016 and has been updated with current information. Learning the results of genetic testing can be a stressful experience for some, but it also has the potential to be empowering. If you are waiting for your genetic test results to come back or are considering …
Genetic testing for hereditary cancer has evolved significantly over the past several years. We are continually learning more information about genes that are associated with increased risks for various cancers; and there are many different genetic tests available that can help you learn more precise information about your patients’ cancer risks, …
As we find more ways to take charge of our health, genetic testing is becoming something that many consider and, in fact, has become easier to access than ever before. An appointment with a doctor or genetic counselor is no longer required to access genetic testing – for some types of genetic tests, it’s now possible to order a test kit online, …
It’s now 1990, and I’ve now had my life-saving heart surgery. After spending nearly a month in the hospital with health complications, I was finally able to go home. After another month at home trying to recover, I decided to head back to work to continue the job and career that I worked long and hard to achieve in executive management and …
Our DNA tells a story — it tells us who we are. With advancements in genetic testing and an increased awareness in personalized healthcare, interest in direct-to-consumer (DTC) testing is on the rise. DTC genetic testing companies have made limited genetic testing for the general population readily accessible to healthy individuals. However, …
Editor’s Note: In honor of Cystic Fibrosis Awareness Month, we asked Jacqueline Washle, Ambry’s Community Outreach Manager, to tell us about the Mauli Ola Foundation, which supports people with cystic fibrosis and other inherited conditions as part of its mission. Did you know that going to the beach is not only a fun pastime for …
Technology is everywhere. It has become pervasive in our lives. Phones and computers became smaller, smaller, and then somehow bigger and bigger again as our phones become our new computers. Increasing technological advances are also propelling healthcare: newer techniques, smarter robotics, and new drugs. Within genetics, testing techniques …
Accurate genetic testing can help clinicians provide more individualized treatments for their patients, and the more genetic information a researcher has access to, the more targeted treatments can be developed. {Read: “For Your Breast Cancer Practice: Data From More Than 60,000 Refines Predisposition Gene Risks”} In March 2016, Ambry’s …
Editor’s Note: We are so pleased to continue introducing new voices into the Ambry patient blog. This week we are honored to have Jon Rodis, patient advocate, tell us what it was like to be diagnosed with Marfan syndrome, an inherited condition that can cause heart problems, many years ago – well before genetic testing became available …
The short answer is: Genetic testing is possible, but depends on other factors. The question of whether genetic testing is possible for patients with a history of hematological cancer comes up often in the clinical setting and in the testing laboratory. This makes sense since genetic testing is performed on DNA isolated from white blood cells …
Editor’s Note: To help support National Autism Awareness Month, we are sharing our interview with Kieran Best, a 14-year-old young man with an autism spectrum disorder. Kieran graciously shared insights into what his day-to-day life is like and offered words of wisdom to others who may be in his situation. Check back in two weeks to read our …
Hereditary diffuse gastric cancer (HDGC) is an inherited cancer syndrome caused by CDH1 gene mutations. It occurs most frequently in Japan and eastern Asia; current incidence in the U.S. is estimated at 10-40 individuals per 100,000.1 Individuals with mutations in the CDH1 gene have up to an 80% lifetime risk of diffuse gastric …
Ambry has continued to provide clinicians with the most relevant and useful information to encourage education about the benefits of genetic testing for patients and ways to streamline genetic testing in clinical practice. At the 2017 SSO Annual Cancer Symposium, Ambry hosted the presentation “On the Cutting Edge: Sharpening Your Genetic Awareness …
On Thursday evening, March 23rd, an audience of more than 100 genetic counselors and geneticists from across the United States listened to Ambry Genetics’ Clinical Genomics Marketing Manager Layla Shahmirzadi, MS, CGC, discuss plans to launch a personalized genomic test for healthy individuals. The talk took place at Events on Jackson venue …
In my role as co-founder of AliveAndKickn, people ask me for my opinion all the time. Topics range from how to manage pain, how to navigate post-cancer survivorship, to whether or not the U.S. will ever become a world soccer powerhouse. (No, I’m not kidding.) I’m not big on giving advice, but I try to answer as honestly as I can. First, …
Actionable medical results are often a key component in deciding a patient’s medical management and specialized treatment options. However, some genetic test results can have unclear implications or Variants of Unknown Significance (VUS), which can often affect a clinician’s medical management plans for their patients. During the 2017 ACMG …
Editor’s Note: In recognition of National Colorectal Cancer Awareness Month, we are re-posting this piece by an Ambry genetic counselor. His many years of clinical experience working with families affected by hereditary colorectal cancer helped him understand the importance of expert care teams, and how they can help you. My name is …
Several years prior to my breast cancer diagnosis, I started to think about the right time to liquidate my business and sell the real estate. At the time, my brother and I owned two Ace hardware stores in the Milwaukee area with approximately 100,000-sq. ft. of retail space, warehouse and offices. I knew it would be a physically daunting undertaking …
Colon cancer is the third most common cancer diagnosed in both men and women in the United States, and more than 95,000 new cases of colon cancer and 39,000 new cases of rectal cancer are estimated for 2017, according to the American Cancer Society. Up to 10% of colorectal cancer is hereditary, or caused by inherited gene mutations. Hereditary …
As a genetic counselor specializing in cancer genetics, I’m happy to be contributing to the Ambry patient blog during National Colorectal Cancer Awareness Month. Colorectal cancer can happen by chance, but it can also be inherited. Your doctor or genetic counselor can evaluate your family history to determine if you should consider genetic testing …
Ribonucleic Acid, otherwise known as RNA, is the messenger that carries instructions for controlling the synthesis of proteins from Deoxyribonucleic Acid (DNA). The central dogma of molecular biology states that “DNA makes RNA makes protein." However, for the proteins, which are the final product, to work properly, the RNA needs to be “edited," …
In honor of Colorectal Cancer Awareness Month, I would like to discuss the most common cause of hereditary colorectal and uterine cancer – Lynch syndrome. In fact, this post is dedicated to my brother Jimmy, who died of colon cancer due to Lynch syndrome at the age of 36. Lynch syndrome is a hereditary cancer condition passed down …
Ever since our initial publication of Sanger sequencing confirmation was featured in The Journal of Molecular Diagnostics, in addition to our accompanying presentation at the National Society of Genetic Counselors conference last fall, Ambry has been touting our superior scientifically-proven genetic testing. Now we are bringing the message that …
Editor’s Note: We are re-posting this entry by Tameron Harvell, a registered nurse practitioner, to raise the profile of “survivor’s guilt” – an issue that can be particularly challenging during the holidays. You’ve just received your cancer genetic testing results and no mutation was found! What a relief …
Editor’s Note: We are re-posting Theresa Smith’s entry to tie in with National Family History Day on Thanksgiving in two weeks in the U.S. Theresa was kind enough to update her piece on the importance of sharing family history and genetic test results, as challenging as it may be at times. Check back here in two weeks …
In honor of Breast Cancer Awareness month, Ambry is proud to support many non-profit foundations and organizations, including the Mauli Ola Foundation’s 3rd annual Battle for the Breasts (B4TB). The B4TB is an online surf contest featuring 16 professional women surfers who are each paired with cancer clinics and/or foundations. Each …
Throughout the healthcare industry, it is known that genetic counselors play a vital role in the care and treatment of patients. Genetic counselors guide patients through the genetic testing journey and provide them and their primary care physician with detailed explanations of their test results. Check out our video that takes potential patients …
The New England Journal of Medicine (NEJM) recently released a study, which concluded that 11.8% of metastatic prostate cancer cases were caused by germline gene mutations leading to hereditary prostate cancer. The study involved 692 men from the United States and United Kingdom who have documented metastatic prostate cancer. Eighty-four germline …
What a perfect time to begin my story — we are in the middle of National Ovarian Cancer Awareness month, as well as National HBOC (hereditary breast and ovarian cancer) Week. I love when things line up like it was all meant to be… Things did not line up for me in October of 2012. While preparing funeral arrangements for my dad …
As a female genetic counselor, I can say I have counseled many men regarding their risk for hereditary cancer. I have seen the different reactions and responses they have had. I have looked for different information (from what I provided to females) to give to them, if it will help. I cannot say I have any idea what it is like to be a man …
There are many different things to consider when deciding whether to have genetic testing. In addition to the impact of the test results on your physical and emotional health and that of your family members (more on that here), you should also consider your insurance coverage and the possibility of discrimination. When I met with patients …
When you learn that you have a BRCA1 or BRCA2 gene mutation, there are naturally questions as to what this will mean for your ongoing medical care and what you will need to do differently. The initial conversation with your healthcare provider will likely include a discussion about the options available to more carefully …
Learning the results of genetic testing can be a stressful experience for some, but it also has the potential to be empowering. If you are waiting for your genetic test results to come back or are considering having genetic testing in the future, hopefully the information in this blog will ease some of the concern you may be experiencing. …
As I sit in the hereditary cancer trenches, I see the negative effects of genetic testing sans certified genetic counseling every single day – and it is an enormous problem. Many of the fears and concerns that people discuss with me could be addressed and ameliorated simply if they spoke with a certified genetic counselor before …
My name is Carin and I’m a genetic counselor at Ambry Genetics. I’ve been working at Ambry for about 2½ years and before that I worked as a clinical genetic counselor seeing patients at a cancer hospital for over six years. I have always had a special interest in hereditary gastrointestinal (GI) cancers. Gastrointestinal cancers, …
Zen master Thich Nhat Hanh believes if people face and embrace their suffering, they will eventually grow from it and possibly turn it into something beautiful and meaningful... Hence the phrase: No mud, no lotus. Five years ago after I was diagnosed with Lynch syndrome, I found myself mired in mud – I had no idea what would emerge …
For a woman being diagnosed with a BRCA2 gene mutation, there is a ton of information specific to cancers for women, but what if you are a man? The amount regarding male breast cancer, hereditary prostate cancer, and hereditary pancreatic cancer is limited. In addition, public awareness about these conditions is limited. Considering …
While it’s difficult for anyone to come to grips with a cancer diagnosis, it becomes more challenging having to share the news with family and friends. Especially when you are a man telling them you have breast cancer. People may look at you with a deer in the headlights stare….men get breast cancer? This was the reaction from many, as …
It was a year after I had tested positive for the BRCA2 gene mutation before I found out about the status of my three children. My oldest, my son, and my youngest daughter were both negative (huge relief). My middle daughter, Jenna, unfortunately tested positive for the same mutation I have. She is 23 years old now and is graduating …
When I was a clinical genetic counselor, I met with many men who had been diagnosed with breast cancer for genetic counseling and genetic testing. Counseling male breast cancer patients about genetics was often very different for me than counseling female breast cancer patients. I think the main reason for that is men and women are different and …
There are many different things to consider when deciding whether to have genetic testing. In addition to the impact of the test results on your physical and emotional health and that of your family members (more on that here), you should also consider your insurance coverage and the possibility of discrimination. When I met with patients as …
After testing positive for a mutation in my BRCA2 gene, I was on high alert. I rushed to all my doctor’s appointments and gathered a lot of information regarding preventive surgery options. I also did a lot of research on the statistics and newer medical studies regarding BRCA1 and BRCA2. I evaluated everything based …
I feel funny writing about sharing genetic test results when I’ve never done it myself, but don’t let that stop you from reading… I’ll draw upon my years in the clinic as a genetic counselor, speaking to many families about this topic, and offer thoughts from my side of the table. I have seen that it’s complicated for some families, …
My mom was first diagnosed with breast cancer in 1989, when breast cancer was still whispered about and long before Angelina Jolie put genetic testing on the Hollywood map. My mom complied with the treatment recommended for her at the time, which included a lumpectomy, chemotherapy and radiation. Eighteen years later, in 2007, I was 34 years old …
According to the National Cancer Institute SEER (Surveillance, Epidemiology, and End Results) stat fact sheet on female breast cancer there were an estimated 12.3% of women living with breast cancer in the United States in 2012. 98.6% of breast cancer survivors diagnosed with early stage breast cancer are alive after 5 years or more. As early …
As a clinical genetic counselor, a big part of my job was educating my patients about the basics of genetics and hereditarycancer. Another equally, if not more, important part of my job was to talk to them about how a diagnosis of cancer, a positive genetic test result, or a combination of the two was impacting their life and those of their …
The funny thing about ‘healthy habits’ is that you can do everything ‘right’, but there are no guarantees in life. For me, breast cancer is hereditary. he·red·i·tar·y Something (like a health problem, like cancer) that is due to inherited genetic changes (mutations), which can be passed from parent to child. I have a BRCA1 gene …
I was diagnosed with a BRCA2 gene mutation on August 1, 2013. My surgery for a complete preventive hysterectomy (to remove my ovaries, Fallopian tubes, cervix, and uterus) was just six weeks later on September 11. I requested to undergo BRCA1/2 genetic testing as a “tie breaker” to help me decide if I should have the surgery, …
So I met all the doctors. What now? All the information and options were given to me, and it was overwhelming, to say the least. I was considering both preventive surgeries (full hysterectomy and preventive bilateral mastectomy (PBM) with reconstruction). I was playing the “odds versus timing” game in my head: “If I wait until I’m X years …
Before my breast cancer diagnosis, I had a brief conversation with my OB/GYN physician regarding my potentially increased breast cancer risk. I was coming up on my 35th birthday, and thought it might be responsible to schedule a baseline mammogram. I don't recall anything remarkable about that conversation with my doctor. She provided me with …